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目的：分析颅咽管瘤ＣＴ、ＭＲＩ特征，探讨影像学表现和病理间的联系，尤其是ＭＲＩ的Ｔ１高信号的产生基础。方法：ＣＴ及ＭＲＩ检查２１例颅咽管瘤患者，均经手术病理证实，囊液进行内容物的镜下分析。结果：实质性３例，囊性、囊实性１８例，其囊液１１例可见Ｔ１加仅像高信号，且不受ＭＲＩ脂肪抑制术影响，病理囊液内均可见胆固醇，Ｔ１高信号的囊液内还可见蛋白物、游离血红蛋白等。结论：ＣＴ、ＭＲＩ相结合可以准确诊断颅咽管瘤，颅咽管瘤囊液内的高信号主要与囊液内的蛋白质有关，与胆固醇类物关系较小。
OBJECTIVE: To analyze the features of CT and MRI in craniopharyngiomas, and to explore the relationship between the imaging findings and the pathology, especially the basis for the generation of T1 high signal in MRI. Methods: 21 cases of craniopharyngioma were examined by CT and MRI. All of them were confirmed by surgery and pathology. The contents of the cyst were analyzed microscopically. Results: Substantial 3 cases, cystic, cystic solid in 18 cases, 11 cases of cystic fluid can be seen only with high signal T1 plus, and not affected by MRI fat suppression, pathological cystic fluid can be seen in cholesterol, T1 high signal The cyst fluid also visible protein, free hemoglobin and so on. Conclusion: The combination of CT and MRI can accurately diagnose craniopharyngioma. The high signal in cyst fluid of craniopharyngioma is mainly related to the protein in cyst fluid, but not to cholesterol.