目的提高对甲状腺功能减退致多肌炎综合征的认识。方法报道3例甲状腺功能减退症致多肌炎综合征的临床特点。男2例,年龄分别为33、38岁;女1例,年龄64岁,均表现为四肢近端肌肉肌无力,肌酶显著升高。结果 2例男性诊断为原发性甲状腺功能减退症,女性为亚临床型甲状腺功能减退症,甲状腺激素替代治疗后效果好。结论临床上对有肌病表现、肌酶显著升高的患者须注意有无甲状腺功能减退症,多发性肌炎样综合征,应注意筛查甲状腺功能。 Objective To raise awareness of hypothyroidism induced polymyositis syndrome. Methods Report of 3 cases of hypothyroidism caused by polymyositis syndrome clinical features. 2 males, aged 33,38 years old; 1 female, aged 64 years, showed muscle weakness in proximal limbs, muscle enzymes were significantly increased. Results Two male patients were diagnosed as primary hypothyroidism, the female was subclinical hypothyroidism, and thyroid hormone replacement therapy was effective. Conclusion Clinical manifestations of myopathy, muscle enzymes were significantly higher in patients with or without attention to hypothyroidism, polymyositis-like syndrome, should pay attention to screening for thyroid function.