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在职业性尘肺的临床中,矽肺结核是一个常见病和多发病。普查发现:硅尘作业工人中结核病的患病率较非硅尘作业者高5～10倍;矽肺患者并发结核率高于硅尘作业工人的3～10倍。因此,提高本病的认识能力,有助于推动硅尘作业防痨的工作,对保护工人健康有着积极的和现实的意义。本文结合国内外有关资料作一概述。原理:矽肺易罹结核的发病原理尚不十分清楚,总的认为,本病的发生机理,不是单一的而是综合因素促成的,如淋巴循环的破坏、血供障碍、生物学坏死、神经损害、组织细胞动员作用和周身的抗结核免疫力低下等。实验证明:矽肺时石英粉尘具有减弱机体对结核感染的免疫能力,以及矽酸有使血液的凝集杀菌力受到影响,导致补体抗体形成
In the clinical practice of pneumoconiosis, silicosis is a common disease and frequently-occurring disease. Census found that: the prevalence of tuberculosis in workers exposed to silica dust is 5 to 10 times higher than that of non-silica dust workers; the incidence of concurrent tuberculosis in silicosis patients is 3 to 10 times higher than that of workers working in silica dust. Therefore, improving the cognitive ability of this disease helps to promote the anti-tuberculosis work and has positive and realistic significance for the protection of workers’ health. This article gives an overview of relevant information at home and abroad. Principle: The pathogenesis of silicosis is not yet very clear, in general, the pathogenesis of this disease is not a single factor but caused by a combination of factors such as the destruction of the lymphatic circulation, blood supply disorders, biological necrosis, nerve damage , Tissue cell mobilization and whole body anti-TB immunity and so on. Experiments show that: quartz dust when silicosis weakens the body’s immune response to tuberculosis infection, and silicic acid has the blood coagulation bactericidal effect, resulting in the formation of antibody complement