论文部分内容阅读
采用放射免疫法测定60例男性失代偿期肝硬化病人的血清雌二醇(E_2)和睾酮(T)。结果表明肝硬化病人血清E_2高于对照组,而T则降低,有极显著性差异(P<0.01)。出血组与非出血组的肝硬化病人血清E_2无显著差异(P>0.05),出血组血清T明显低于无出血组(P<0.01)。提示上消化道大出血后肝硬化病人血清T降低E_2升高反馈抑制了垂体-睾丸的功能,推测同时伴有垂体-睾丸间质细胞功能的进一步受损。
Serum estradiol (E2) and testosterone (T) were measured in 60 male patients with decompensated cirrhosis by radioimmunoassay. The results showed that patients with cirrhosis serum E 2 higher than the control group, while T decreased, with a very significant difference (P <0.01). There was no significant difference in serum E_2 between hemorrhagic and non-hemorrhagic cirrhotic patients (P> 0.05). Serum T in hemorrhagic group was significantly lower than that in non-hemorrhagic group (P <0.01). Prompted the upper gastrointestinal hemorrhage patients with cirrhosis of serum T decreased E2 increased feedback inhibition of pituitary - testicular function, suggesting that accompanied by pituitary - testicular interstitial cells further damage.