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目的探讨中医中药对紫癜性肾炎(HSPN)治疗效果,为HSPN防治提供有益的参考。方法选取2009年1月至2012年12月期间,确诊为HSPN的126患者,采取病例对照研究方法,按病历号单双数随机分为两组,对照组60例,治疗组66例,对照组结合临床分型,给予雷公藤多苷、血管紧张素转换酶抑制剂、皮质激素、免疫抑制剂、抗血小板聚集、抗凝等传统的西医方法治疗,治疗组通过中医辨证,结合临床分型,在西医治疗的基础上联合中医中药治疗,中药的组伍采取生物共振优化选择。结果经3年随访治疗组总有效62例(93.9%),对照组总有效42例(70.0%),两组比较差异有统计学意义(P<0.01)。结论生物共振有利于中药的优选,组伍,更利于发挥中医中药的优势;采用中西医结合的方法治疗儿童HSPN有显著疗效。
Objective To explore the therapeutic effect of traditional Chinese medicine on purpura nephritis (HSPN) and to provide a useful reference for the prevention and treatment of HSPN. Methods A total of 126 patients diagnosed with HSPN from January 2009 to December 2012 were selected and randomly divided into two groups according to the case-control study data. Sixty patients in the control group, 66 in the treatment group and 66 in the control group Combined with clinical classification, given the traditional Chinese medicine treatment of tripterygium glycosides, angiotensin converting enzyme inhibitors, corticosteroids, immunosuppressive agents, anti-platelet aggregation, anticoagulation, the treatment group by TCM syndrome differentiation, combined with clinical classification, On the basis of Western medicine treatment combined with traditional Chinese medicine, Chinese medicine team to optimize the selection of biological resonance. Results The total effective rate was 62 (93.9%) in the treatment group and 42 (70.0%) in the control group after 3 years of follow-up. The difference between the two groups was statistically significant (P <0.01). Conclusion Bioresonance is beneficial to the optimization of traditional Chinese medicine, and it is more conducive to exert the advantages of traditional Chinese medicine. The treatment of HSPN in children with the combination of TCM and Western medicine has obvious curative effect.