论文部分内容阅读
目的探讨吸烟、饮酒、慢性病、空腹血糖水平、尿酸等危险因素与泌尿系结石形成的相关性。方法通过1∶1匹配病例-对照设计,随机从武汉大学中南医院泌尿外科2015年5月至11月就诊459名泌尿系结石患者中抽取150例,以能获得完整数据信息的患者作为病例组,对照组为性别、民族、婚姻状态与病例组匹配的泌尿科非结石住院患者。采用单变量分析及条件Logistic的方法对两组数据进行统计分析。结果共纳入125例泌尿系结石患者和125例对照患者。泌尿系结石患者高峰发病年龄为50~70岁;男性占所有结石患者的70.75%;单侧结石占所有结石患者的62.24%。多因素回归分析结果显示,仅高血尿酸与发生泌尿系结石相关[OR=5.19,95%CI(2.27,11.91),P<0.01]。结论高尿酸血症是发生泌尿系结石的高危因素之一。
Objective To investigate the relationship between smoking, alcohol drinking, chronic diseases, fasting blood glucose, uric acid and other risk factors and urolithiasis. Methods A 1: 1 matched case-control design was used to randomly select 150 patients from 459 patients with urinary calculi from Department of Urology, Zhongnan Hospital of Wuhan University from May to November 2015. Patients with complete data were selected as case group, The control group was gender, nationality, marital status and case group matching urinary non-stone hospitalized patients. Univariate analysis and conditional Logistic method were used to analyze the two groups of data. Results A total of 125 patients with urolithiasis and 125 controls were enrolled. Patients with urolithiasis peak age at onset of 50 to 70 years; men accounted for 70.75% of all patients with stones; unilateral stones accounted for 62.24% of all patients with stones. Multivariate regression analysis showed that hyperuricemia was associated with urolithiasis only [OR = 5.19, 95% CI (2.27, 11.91), P <0.01]. Conclusion Hyperuricemia is one of the risk factors of urolithiasis.