用灌胃法观察了微量元素锌、硒、锗对小鼠免疫功能的影响。结果 :锌 (8mg/ kg)、硒 (0 .1mg/kg)、锗 (10 0 mg/ kg)均可显著提高小鼠巨噬细胞吞噬百分率及吞噬指数 ,且加锌组较加锗组的作用更为明显 (P <0 .0 1) ;亦可显著提高小鼠 E-花结形成、淋巴细胞增殖反应和 IL - 6活性 (P <0 .0 1)。各实验组之间无明显差异。提示 :适量的锌、硒、锗可提高机体巨噬细胞吞噬功能 ,增强细胞免疫功能和IL - 6活性。 The effects of trace elements zinc, selenium and germanium on immune function in mice were observed by gavage method. Results: The phagocytic percentage and phagocytic index of macrophages in mice were significantly increased by zinc (8 mg / kg), selenium (0.1 mg / kg) and germanium (100 mg / kg) (P <0.01). E-rosette formation, lymphocyte proliferation and IL-6 activity in mice were also significantly increased (P <0.01). No significant difference between the experimental groups. Tip: The proper amount of zinc, selenium and germanium can enhance phagocytic function of macrophages and enhance cellular immunity and IL - 6 activity.