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氯喹在临床上广泛应用于治疗疟疾及阿米巴肝脓疡。由于它具有免疫抑制效能,在治疗自身免疫性疾患中亦有应用。现报告1例由氯喹引起的心原性脑缺血综合征。患者女性,23岁,因不规则畏冷发烧一个多月,于1978年3月26日入院。经同位素肝扫描等检查诊断为左叶肝脓疡。在用抗菌素的同时,以氯喹0.25克,一日3次口服。4月7日晚11时许(氯喹总量4.75克),患者突然神志不清,全身抽搐约1分钟后恢复。4月8日继服氯喹,于晚上10时30分(氯喹总量
Chloroquine widely used in the clinical treatment of malaria and amoebiasis abscess. Because of its immunosuppressive potency, it is also used in the treatment of autoimmune disorders. A case of chloroquine-induced cardiogenic cerebral ischemic syndrome is now reported. Female, 23, was admitted to hospital on March 26, 1978 due to irregular fever and fever for more than a month. Isotopic liver scan examination diagnosed as left lobe liver abscess. With antibiotics at the same time, chloroquine 0.25 grams, 3 times a day orally. 11 o’clock on April 7 (chloroquine total 4.75 grams), the patient suddenly unconscious, systemic convulsions recovered after about 1 minute. Following the submission of chloroquine on 8 April, at 10:30 pm (the total amount of chloroquine