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血管内皮细胞生长因子(vascular endothelial growth fac-tor,VEGF)是于1989年从牛垂体滤泡星状细胞的条件培养基中纯化,是一种与血管生长有关的特异性生长因子。研究表明VEGF是血管内皮细胞的有丝分裂原,在生理和病理情况下均可表达,能够特异性地作用于血管内皮细胞上的特异性
Vascular endothelial growth factor (VEGF) was purified from conditioned media of bovine pituitary fibroblasts in 1989 and is a specific growth factor associated with vascular growth. Studies have shown that VEGF is a mitogen of vascular endothelial cells, can be expressed in both physiological and pathological conditions, and can specifically act on the specificity of vascular endothelial cells