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目的观察特布他林联合布地奈德雾化吸入治疗重症哮喘的临床效果。方法将医院呼吸内科治疗的重症哮喘患者76例随机分为观察组和对照组,每组38例。2组均给予常规对症治疗,对照组加用布地奈德雾化吸入治疗,观察组加用特布他林联合布地奈德雾化吸入治疗,比较2组患者的治疗效果、症状改善时间以及肺功能情况。结果观察组治疗有效率为94.7%高于对照组的78.9%(P<0.05);观察组治疗后喘息、呼吸困难、咳嗽、肺部哮鸣音消失时间均短于对照组(P<0.05);观察组FEV1、FVC、PEF明显较对照组改善,差异有统计学意义(P<0.05)。结论特布他林联合布地奈德雾化吸入治疗重症哮喘疗效显著,效果优于单一用药,可快速缓解症状,减少因单一用药,造成的治疗时间长,费用高的问题,改善肺功能,具有积极的临床意义。
Objective To observe the clinical effect of terbutaline combined with budesonide inhalation on severe asthma. Methods A total of 76 patients with severe asthma treated by medical resuscitation were randomly divided into observation group and control group, with 38 cases in each group. The two groups were given conventional symptomatic treatment, the control group plus budesonide inhalation therapy, the observation group plus terbutaline combined with budesonide inhalation therapy, the treatment effect of two groups were compared, the time to symptom improvement and lung Functional situation. Results The effective rate of observation group was 94.7%, which was significantly higher than that of control group (78.9%, P <0.05). The wheezing, dyspnea, cough and lung wheeze disappeared in the observation group were shorter than those in the control group (P <0.05) ; FEV1, FVC, PEF in observation group were significantly improved compared with control group, the difference was statistically significant (P <0.05). Conclusion Terbutaline combined with budesonide inhalation is effective in treating severe asthma with better effect than single administration, which can relieve symptoms quickly, reduce the problem of long treatment time and high cost due to single drug use, improve pulmonary function, Positive clinical significance.