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毁损家兔腰段脊髓后观察电针“长强穴”降热效应的影响。实验结果表明;电针发热家兔“长强穴”,对发热效应具有显著的抑制作用。60分钟时△T℃为0.23±0.07;TRI_4为0.61±0.03,与LP组比较(△T℃为0.68±0.06;TRI_4为2.10±0.05)分别具有高度显著性(P<0.01)或显著性(P<0.05)。此时,脑脊液中cAMP含量,在60分钟时(为20.50±1.87nmol/L)与LP组比较(28.59±2.77nmol/L),具有高度显著性差异(P<0.01)。但在毁损腰段脊髓后,再电针发热家兔“长强穴”,其发热效应并未受到抑制,60分钟时△T℃为0.66±0.10;TRI_1为0.62,与LP组比较(△T℃为0.68±1.0;TRI_1为0.65)则无显著性差异(P>0.05)。州时,脑脊液中cAMP含量显著增加(27.28±2.12nmol/L),与LP组比较(28.59±2.27nmol/L)无显著性差异(P>0.05)。单纯腰段脊髓毁损对家兔体温,LP发热效应有一定影响,但对脑脊液中cAMP含量在60分钟无明显影响。由此,作者推论:电针“长强穴”的降热效应和机制,很可能是电针该部位时所引起的神经冲动,通过脊髓传入中枢神经系统,主要传入PO/AH区的神经元细胞,以某种方式导致cAMP生成减少,抑制“调定点”上移,故出现发热抑制效应。
After damaging the lumbar spinal cord in rabbits, the effects of electro-acupuncture “long strong points” on the cooling effect were observed. The experimental results show that the EA rabbit fever “long strong points” has a significant inhibitory effect on the fever effect. At 60 minutes, ΔT°C was 0.23±0.07; TRI_4 was 0.61±0.03, which was highly significant (P<0.01) or significant (P<0.01) compared with the LP group (ΔT°C was 0.68±0.06; TRI_4 was 2.10±0.05). P<0.05). At this time, the cAMP content in cerebrospinal fluid was significantly higher at 60 minutes (20.50±1.87 nmol/L) than in the LP group (28.59±2.77 nmol/L) (P<0.01). However, after the lumbar spinal cord was destroyed, the febrile electroacupuncture was a “long strong point” in rabbits. The fever effect was not suppressed. At 60 minutes, △T°C was 0.66 ± 0.10; TRI_1 was 0.62, which was compared with the LP group (△T °C was 0.68±1.0; TRI_1 was 0.65), but there was no significant difference (P>0.05). At the time of state, cAMP content in cerebrospinal fluid increased significantly (27.28±2.12 nmol/L), and there was no significant difference (28.59±2.27 nmol/L) compared with LP group (P>0.05). The lumbar spinal cord injury alone had a certain effect on the body temperature and LP fever, but it had no significant effect on the cAMP content in cerebrospinal fluid at 60 minutes. Therefore, the authors reasoned that the effect and mechanism of the cooling effect of the electro-acupuncture “long strong points” may be the nerve impulses caused by electro-acupuncture at the site, and the nerves that pass through the spinal cord and enter the central nervous system and mainly pass into the PO/AH area. Metacytosis, in some way, leads to a decrease in cAMP production and inhibits the “adjustment point” upwards, so that a fever-suppressing effect occurs.