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目的探讨瘦素对胎儿生长发育的影响。方法选取胎龄满37周至不足42周足月并且经阴道自然分娩的新生儿102例,根据出生体重分为3组,分别检测脐血瘦素,进而分析瘦素与不同体重组新生儿之间的相关性。结果大于胎龄儿组的脐血瘦素含量高于其他两组,其差异有显著性差异(P<0.05)。结论脐血瘦素水平与不同体重足月新生儿出生时的体重均呈正相关性,瘦素水平可以反映胎儿宫内生长发育情况。
Objective To investigate the effect of leptin on fetal growth and development. Methods Totally 102 neonates with gestational age ranging from 37 weeks to less than 42 weeks and spontaneous vaginal delivery were divided into 3 groups according to their birth weight. Cord blood leptin levels were measured respectively, and then between leptin and different weight neonates Relevance. Results The cord blood leptin content in children with gestational age was higher than that in other two groups, with significant difference (P <0.05). Conclusion There is a positive correlation between cord blood leptin level and birth weight of newborns with different body weights. Leptin level can reflect the intrauterine growth and development.