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作者于1971年春季麻疹流行中,研究一岁前接种麻疹疫苗儿童的免疫状况。 147名一岁前接种麻疹活疫苗的儿童,经证明80%有麻疹血凝抑制抗体,所用的疫苗类型对抗体或几何平均值无关。此外24名一岁以后接种麻疹疫苗儿童中有20名麻疹血凝抑制抗体为阳性,抗体几何平均值为204,比一岁前接种疫苗者明显地高(P<0.01)。因而证明愈幼小接种疫苗,其抗体趋向于低滴度,如9月龄以前接种疫苗的儿童,44%的抗体滴度≤1:10,9~11月龄接种疫苗者≤1:10为33%,而一岁以后接种疫苗者抗体滴度≤1:10
In the spring of 1971 measles epidemic, the author studied the immunological status of children vaccinated against measles one year before. Of the 147 children vaccinated against measles live before the age of one year, 80% had evidence of measles-haemagglutination-inhibiting antibodies and the type of vaccine used had no effect on antibody or geometric means. In addition, 20 of the 24 measles vaccine-immunized children after the first year of age were positive for hemagglutination-inhibiting antibodies with a geometric mean of 204 antibodies, significantly higher than those vaccinated before the first year of age (P <0.01). Thus proving the younger the vaccination, the antibody tends to low titers, such as vaccination of children before the age of 9 months, 44% of the antibody titers ≤ 1: 10, 9 to 11 months of vaccination ≤ 1: 10 33 %, While the one-year-old vaccinated antibody titer ≤ 1: 10