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本校学生27名,男生15名,女生12名,年龄15~20岁。平素健康,无胃肠道症状。应用常规胃镜检查,并在胃窦部活检粘膜3~4块,分别进行幽门弯曲菌培养,涂片革兰氏染色和Warthin—Starry银染色查找细菌,HE染色作组织学诊断。结果:27例中胃炎的检出率,胃镜诊断为51.8%(13/27);组织学诊断为74.1%(20/27),其中浅表性胃炎伴灶性萎缩2例。幽门弯曲菌阳性者18例,占66.7%,均发生在有组织学胃炎的患者。组织学正常者7例,无一例检出此菌。两组相差非常显著(P<0.01)。提示幽门弯曲菌与慢性胃炎相关,认为幽门弯曲菌感染很可能是这些学生慢性胃炎的病因。同时也说明,这种与
27 students, 15 boys and 12 girls, aged 15 to 20 years old. Usually healthy, no gastrointestinal symptoms. Normal gastroscopy was performed and 3 to 4 mucosa were biopsied in the antrum. Bacillus pylori, smear Gram stain and Warthin-Starry silver staining were used to detect the bacteria. HE staining was used for histological diagnosis. Results: The detection rate of gastritis in 27 cases was 51.8% (13/27) in gastroscopy, and 74.1% (20/27) in histological diagnosis, of which 2 cases were superficial gastritis with focal atrophy. Campylobacter pylori positive in 18 cases, accounting for 66.7%, all occurred in patients with histological gastritis. Histology was normal in 7 cases, no case detected this bacterium. The difference between the two groups was significant (P <0.01). Suggesting that Campylobacter pylori associated with chronic gastritis, Campylobacter jejuni infection that may be the cause of these students chronic gastritis. Also shows that this and