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作者采用直接放免法测定了肾功能损害病人的心房利钠肽(human atrial natriuretic pdypeptide,hANP)血浆浓度。研究对象分为血液透析组(HD)、非血液透析组(NHD)和正常对照组。HD 组56例,其中男30例,女26例,年龄19～68(平均62.5)岁。血透时间为43.9±5.5个月。NHD 组13例,其中男7例,女6例,年龄17～69(平均47.6)岁。研究对象均卧床至少30分钟后抽血检查,结果平均血浆 hANP(±SE)为404±23pg/ml;正常对照组(n=15)hANP 为236±11pg/ml;两者比较有非常显著性差异(P<
The authors used direct radioimmunoassay to determine plasma concentrations of human atrial natriuretic pdypeptide (hANP) in patients with impaired renal function. Subjects were divided into hemodialysis group (HD), non-hemodialysis group (NHD) and normal control group. There were 56 cases in HD group, including 30 males and 26 females, ranging in age from 19 to 68 (average 62.5 years). Hemodialysis time was 43.9 ± 5.5 months. Thirteen NHD patients, including 7 males and 6 females, aged from 17 to 69 (average 47.6 years). The subjects were all in bed for at least 30 minutes after the blood test, the results of the average plasma hANP (± SE) was 404 ± 23pg / ml; normal control group (n = 15) hANP 236 ± 11pg / ml; the two were very significant Difference (P <