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睾丸淋巴瘤约占睾丸肿瘤的5％;原发性者更为少见。现报告11例,年龄3～69岁,其中3例为儿童。病程20天～2年。均为单侧性(右6,左5)。 病理材料:肿瘤大小从4×3×3cm～10×5×5cm。多数境界清楚,部分有包膜,质实,切面灰红或谈黄白色,鱼肉状。一例见分叶状结构,并有囊性变及出血。二例副睾肿大呈结节状。 显微镜检查:全部病例均见肿瘤细胞呈弥漫性分布于曲细精管间,癌细胞大小较一致,胞浆较少。按非何杰金氏淋巴瘤工作分类(修订洛阳方案,1982年上海),小核裂细胞性4例(2例为儿童)、大核裂细胞性2例、淋巴母细胞性2例(1例为儿童)、淋巴浆细胞样2例、小无裂细胞性1例。瘤细胞核分裂较小。5例可见“星空现象”,1例有较明显的纤维化。9例曲细精管不同程度萎缩或数目减少,2例曲细精管消失,2例癌细胞浸润副睾管,9例浸润白膜。
Testicular lymphoma accounts for about 5% of testicular tumors; primary is more rare. Now report 11 cases, aged 3 to 69 years, of which 3 were children. Duration of 20 days to 2 years. Unilateral (right 6, left 5). Pathological materials: tumor size from 4 × 3 × 3cm ~ 10 × 5 × 5cm. Most of the realm is clear, part of the envelope, texture, face gray or yellow and white, fish-like. A case of lobulated structure, and cystic degeneration and bleeding. Two cases of epididymal nodules. Microscopic examination: All cases were found diffuse distribution of tumor cells in the seminiferous tubules, cancer cells more consistent size, less cytoplasm. According to the classification of non-Hodgkin’s lymphoma (revision of Luoyang scheme, Shanghai in 1982), 4 cases of small nucleated cell (2 cases were children), 2 cases of large cell nuclear degeneration and 2 cases of lymphoblastic Cases of children), lymphoid plasmacytoid in 2 cases, small non-cancerous in 1 case. Tumor cell nuclear fission smaller. 5 cases of visible “Star phenomenon”, 1 case had more obvious fibrosis. 9 cases of seminiferous tubules atrophy or decreased in varying degrees, 2 cases of seminiferous tubules disappeared, 2 cases of cancer cells infiltration of the testis, 9 cases of infiltration of the white membrane.