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目的探讨首次脑梗死(ACI)患者超敏C-反应蛋白(hsCRP)与动脉硬化指数(AIP)的相关性及其临床意义。方法随机选取60例首次脑梗死患者,对其进行神经功能缺损评分,检测各组患者血清hsCRP及TCH,TG,HDL-C,LDL-C等水平,计算动脉硬化指数;选取35例体检健康者作为对照组。结果ACI患者血清hsCRP,TG水平及AIP明显高于对照组,并且无论是脑梗死组还是对照组,hsCRP水平与动脉硬化指数无相关性。结论hsCRP与脑梗死的发生有密切关系,可能是独立于TG和L-DLC,H-DLC以外的脑梗死相关危险因素;AIP与脑梗死有关。
Objective To investigate the correlation between hsCRP and atherosclerosis index (AIP) in patients with first cerebral infarction (ACI) and its clinical significance. Methods Sixty patients with first cerebral infarction were randomly selected and scored for neurological deficit. Serum levels of hsCRP, TCH, TG, HDL-C and LDL-C were measured to calculate the arteriosclerosis index. 35 healthy volunteers As a control group. Results The serum levels of hsCRP, TG and AIP in ACI patients were significantly higher than those in control group. There was no correlation between hsCRP level and arteriosclerosis index in cerebral infarction group and control group. Conclusion hsCRP is closely related to the occurrence of cerebral infarction, which may be related to cerebral infarction independent of TG, L-DLC and H-DLC. AIP is associated with cerebral infarction.