论文部分内容阅读
甲状腺激素能使很多种组织的耗氧量增加,使很多激素和代谢物的更新加快。它能影响很多脏器系统的代谢和功能,并与蛋白质和脂质代谢密切关联。甲状腺激素能增强儿茶酚胶的作用,也能促进生长激素等特殊蛋白质的合成。在动物实验中,对新生动物的生长和发育有很大影响,对两栖动物的变态也有重要作用。人体常由于甲状腺激素的缺乏或过多而产生疾病,幼年时甲状腺功能低下(甲低),将导致中枢神经系统和机体的发育不良。甲状腺激素的这种多样化生物效应究竟是通过什么样的生化作用机制产生的呢?约在十年前,我们开始了这方面的工作。对碘化甲状腺原氨酸中
Thyroid hormones increase the oxygen consumption of many tissues and accelerate the update of many hormones and metabolites. It affects the metabolism and function of many visceral systems and is closely linked to protein and lipid metabolism. Thyroid hormone can enhance the role of catechins, but also can promote the synthesis of special proteins such as growth hormone. In animal experiments, the growth and development of newborn animals have a great impact on the metamorphosis of amphibians also play an important role. Hypothyroidism (hypothyroidism) in childhood is often caused by a deficiency or excess of thyroid hormones in the human body, which can lead to dysplasia in the central nervous system and the body. What kind of biochemical mechanism of thyroid hormones this diversified biological effect through what mechanism? About 10 years ago, we started this work. For iodinated thyronine