论文部分内容阅读
目的:分析南京地区绝经后妇女人乳头瘤病毒(HPV)感染率、感染分型及年龄分布情况,为绝经后妇女宫颈癌防治提供依据。方法:用凯普导流杂交技术对1 060名绝经后妇女的宫颈脱落细胞标本进行HPV分型检测,分析HPV感染率、分型及年龄分布等特点。结果:1 060份宫颈脱落细胞标本中共检出275例HPV感染,总感染率为25.94%(275/1 060);21种HPV亚型中除了42亚型外,其余均检出;高危型感染率为24.15%(256/1 060),低危型感染率为5.37%(57/1 060),总体单一感染为176例(16.60%),多重感染为99例(9.34%)。提示绝经后妇女HPV感染高发,且年龄分组后各组间HPV感染率差异没有统计学意义(P>0.05)。结论:南京地区绝经后妇女HPV感染率高,并且以高危单一性为主。
Objective: To analyze the HPV infection rate, infection type and age distribution of postmenopausal women in Nanjing area, and provide evidence for prevention and treatment of cervical cancer in postmenopausal women. Methods: HPV types were detected in 1 060 women with cervical exfoliated cells by flow-tip hybridization and HPV infection rate, typing and age distribution were analyzed. Results: A total of 275 HPV infections were detected in 1 060 cervical exfoliated cells with a total infection rate of 25.94% (275/1 060). All 21 HPV subtypes were detected except 42 subtypes. The rate of low-risk infection was 5.37% (57/1 060). The overall single infection was 176 (16.60%) and the multiple infection was 99 (9.34%). Prompted the high incidence of HPV infection in postmenopausal women, and there was no significant difference in HPV infection rates among the groups after age grouping (P> 0.05). Conclusion: The HPV infection rate of postmenopausal women in Nanjing area is high, and the predominance of high-risk monosomy is the most common.