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目的:了解健康儿童社区获得性耐甲氧西林金黄色葡萄球菌(MRSA)的耐药性及影响因素。方法:收集广州市荔湾区部分健康儿童的相关资料及鼻拭子样本,对耐甲氧西林金黄色葡萄球菌阳性菌株进行抗生素药物敏感性检测。结果:从463份标本中分离出金葡菌144例,检出率为31.1%,其中16株为MRSA,占3.5%。87.5%MRSA呈多药耐药状态,对青霉素、氯霉素、四环素、红霉素、克林霉素均耐药。MRSA携带主要与儿童参加日托所有关(P<0.05)。结论:广州荔湾区幼儿园健康儿童社区获得性MRSA携带率较高,菌株的多药耐药状态不容忽视。
Objective: To understand the community-acquired resistance to methicillin-resistant Staphylococcus aureus (MRSA) in healthy children and its influencing factors. Methods: The relevant data and nasal swab samples of some healthy children in Liwan District of Guangzhou were collected to test the antibiotic susceptibility of methicillin-resistant Staphylococcus aureus positive strains. Results: Staphylococcus aureus was isolated from 463 specimens, with a detection rate of 31.1%. Among them, 16 strains were MRSA, accounting for 3.5%. 87.5% MRSA was multidrug resistant and resistant to penicillin, chloramphenicol, tetracycline, erythromycin and clindamycin. MRSA was mainly associated with children attending daycare (P <0.05). Conclusion: Community-acquired MRSA carrying rate of healthy children in Liwan district kindergarten in Guangzhou is relatively high, and multi-drug resistant status of strains can not be ignored.