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为研究肿瘤坏死因子α（ＴＮＦα）在慢性肝病发病机制中的作用，用ＥＬＩＳＡ 法测定了慢性肝病患者血清中ＴＮＦα浓度。结果表明，各种慢性肝病患者血清ＴＮＦα水平明显高于正常对照组（Ｐ＜ ０－０１）。这为临床诊断和治疗慢性肝病提供了理论基础。
To study the role of tumor necrosis factor-α (TNF α) in the pathogenesis of chronic liver disease, ELISA method was used to determine the concentration of serum TNF α in patients with chronic liver disease. The results showed that a variety of patients with chronic liver disease serum TNF α levels were significantly higher than the normal control group (P <0-01). This provides a theoretical basis for clinical diagnosis and treatment of chronic liver disease.