周细胞包裹血管内皮细胞形成血管腔,具有重要的功能,周细胞减少导致出现血管扩张、渗血,导致水肿、新生血管等病变。近年研究发现周细胞通过多种信号通路对于视网膜血管调节、代谢等方面起着重要的作用,具有调节内皮细胞增殖、分化,调控新生血管生长及稳定性等多种功能。现就周细胞在视网膜新生血管疾病中的研究现状予以综述。 Pericyte wraps vascular endothelial cells to form vascular cavities, which have important functions. Pericyocytopenia leads to vasodilation, oozing, edema and neovascularization. In recent years, studies have found that pericytes play an important role in the regulation and metabolism of retinal blood vessels through a variety of signaling pathways, and have the functions of regulating the proliferation and differentiation of endothelial cells and regulating the growth and stability of new blood vessels. The status of research on pericytes in retinal neovascular diseases is reviewed.