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葛根素是中药葛根的有效成分 ,对心脑血管疾病具有广泛的药理作用[1] 。研究表明 ,经皮腔内冠状动脉成型术(ＰＴＣＡ)后最主要的并发症为再狭窄 ,其主要表现为血管平滑肌细胞 (ＶＳＭＣ)的增殖和迁移以及细胞外基质的增多 ,而ＶＳＭＣ和巨噬细胞的凋亡功能失调和 (或 )凋亡小体
Puerarin is an active ingredient of Pueraria radix and has extensive pharmacological effects on cardiovascular and cerebrovascular diseases [1]. Studies have shown that the main complication after percutaneous transluminal coronary angioplasty (PTCA) is restenosis, which is mainly manifested by proliferation and migration of vascular smooth muscle cells (VSMC) and increase in extracellular matrix, and VSMC and macrophage Apoptosis in cells and (or) apoptotic bodies