为了探讨间质治疗对肿瘤微血管的影响，作者观察了移植性小鼠Ｓ１８０实体瘤在３２磷玻璃微球间质治疗后的血管铸型及墨汁灌注切片。结果表明：治疗后肿瘤毛细血管数量减少，排列不规则，血管扩张；瘤周血管密度下降。提示间质治疗同外照射一样对肿瘤微血管有损伤作用，而微血管的损伤是影响治疗效果的重要影响因素 In order to investigate the effect of interstitial therapy on tumor microvessels, the authors observed vascular casts and ink perfusion slices of S180 solid tumor in transplanted mice after 32 P glass microsphere interstitial therapy. The results showed that: after treatment, the number of tumor capillaries decreased, irregular arrangement, blood vessels dilated; peritumoral vascular density decreased. Tip interstitial therapy with the same external radiation on tumor microvascular damage, and microvascular damage is an important factor affecting the treatment effect