本文就有关甘露醇的临床应用情况作一简介,以供参考。 1.甘露醇在降低颅内压中的应用:甘露醇静脉注射20min后,使血浆渗透压升高,能把细胞间液中的水迅速移入血管内,而使组织脱水。用药20min左右,颅内压开始下降,2～3h达高峰,其作用维持6h左右,颅内压可降低46～55%。用法:20%甘露醇溶液1g/kg/次,于15min内快速静注或0.5h内滴注完,每6～12h重复1次,也可在甘露醇两次用 This article on the clinical application of mannitol make an introduction for reference. 1. Mannitol in the reduction of intracranial pressure in the application: mannitol intravenous injection 20min, the plasma osmolality, the fluid in the intercellular fluid can quickly move into the blood vessels, leaving the tissue dehydration. Medication 20min or so, intracranial pressure began to decline, 2 ~ 3h reached its peak, the role of maintaining about 6h, intracranial pressure can be reduced 46 ~ 55%. Usage: 20% mannitol solution 1g / kg / time, rapid intravenous infusion within 15min or within 0.5h infusion, repeated every 6 ~ 12h, can also be used twice in mannitol