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目的了解郑州大学女性教职工高脂血症发病率及各血脂测量指标的临床水平,探讨体质指数(BMI)和腰臀比(WHR)与高脂血症的关系。方法对郑州大学2008年进行健康体检的2 098名女性教职工体检资料进行统计分析,采用Logistic回归进行相关影响因素分析。结果女性教职工总体人群高脂血症患病率为40.1%,随着年龄增加人群血脂水平逐渐升高(P<0.01);与BMI、WHR正常人群比较,超重及肥胖人群血脂水平均明显升高(P<0.01);高甘油三酯血症在<35岁人群中所占比例为59.1%,>55岁人群中为33.6%,随着年龄的增加,此类型比例逐渐降低;高胆固醇血症和混合型高脂血症所占比例均随年龄逐渐增加;多因素Logistic回归分析结果表明,年龄、BMI、WHR是高脂血症的危险因素,相对危险度分别为1.059(95%CI=1.051～1.067)、1.147(95%CI=1.106～1.189),45.526(95%CI=4.581～452.433),其中WHR的作用最明显。结论年龄、BMI及WHR水平与高脂血症密切相关,WHR相关性更明显。
Objective To understand the incidence of hyperlipidemia and serum lipid levels in female faculty in Zhengzhou University and to explore the relationship between body mass index (BMI) and waist-hip ratio (WHR) and hyperlipidemia. Methods The physical examination data of 2 098 female faculty members who conducted a physical examination in 2008 in Zhengzhou University were statistically analyzed. Logistic regression was used to analyze the influencing factors. Results The prevalence of hyperlipidemia in the general female faculty was 40.1%. The level of blood lipid increased gradually with age (P <0.01). Compared with the normal BMI and WHR groups, the lipid levels of overweight and obese people were significantly increased (P <0.01). The prevalence of hypertriglyceridemia was 59.1% in those <35 years old and 33.6% in those> 55 years old. The proportion of hypertriglyceridemia gradually decreased with age, The proportions of disease and mixed hyperlipidemia increased with age. Multivariate Logistic regression analysis showed that age, BMI and WHR were risk factors of hyperlipidemia with relative risk of 1.059 (95% CI = 1.051 ~ 1.067), 1.147 (95% CI = 1.106 ~ 1.189) and 45.526 (95% CI = 4.581 ~ 452.433), respectively. WHR played the most significant role. Conclusion Age, BMI and WHR levels are closely related to hyperlipidemia and WHR is more obvious.