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目的:观察辛伐他汀治疗不稳定型心绞痛伴高脂血症的临床疗效。方法:将80例符合标准的不稳定型心绞痛伴高脂血症的患者随机分为两组,每组40例,两组患者无显著差异,具有可比性。对照组给予常规治疗和饮食控制,治疗组在对照组治疗方法的基础上,给予辛伐他汀进行治疗。治疗24周,观察治疗前后两组患者心绞痛症状的发作次数和频率、心电图ST段改变及血脂水平。结果:治疗组患者的血脂水平显著降低,临床总有效率优于对照组。结论:辛伐他汀对不稳定型心绞痛伴高脂血症患者具有良好疗效。
Objective: To observe the clinical efficacy of simvastatin in the treatment of unstable angina with hyperlipidemia. Methods: Eighty patients with unstable angina pectoris and hyperlipidemia were randomly divided into two groups, 40 cases in each group. There was no significant difference between the two groups, which is comparable. The control group was given routine treatment and diet control. The treatment group was treated with simvastatin on the basis of the control group. After 24 weeks of treatment, the incidence and frequency of angina pectoris, changes in ST segment of ECG and blood lipid level in both groups were observed before and after treatment. Results: The level of serum lipids in the treatment group was significantly lower than that in the control group. Conclusion: Simvastatin has a good effect on patients with unstable angina and hyperlipidemia.