龋齿的预防,是国内外口腔医务工作者所着重致力的工作之一。过去已经有好多方法,比较普遍的是氟防龋。近年来,又提出了一些新的预防方法。例如用葡聚糖介酶或氯巳定消除菌斑;抗菌素消灭致龋细菌及防龋涂料的试用等。用免疫方法预防龋病,好多年以前就有人提出过,但未引起足够的重视。近年来由于对牙菌斑以及菌斑中致龋链球菌作了大量的研究工作,加之最近十多年免疫学的迅速发展,因而使人们想到有可能用免疫的方法来控制龋病的发生和发展。 Dental caries prevention is one of the focuses of oral and medical workers at home and abroad. In the past there are many ways, the more common is fluoride anti-caries. In recent years, some new prevention methods have been proposed. For example, dextranase or clomipamide eliminate plaque; antimicrobial elimination of cariogenic bacteria and anti-caries coating trial. Prevention of dental caries by immunization has been proposed many years ago, but did not attract enough attention. In recent years due to plaque and plaque in the caries-making streptococci have made a lot of research work, combined with the rapid development of immunology over the past decade, so that people think of the possibility of using immunization to control caries and development of.