CLINICAL SIGNIFICANCES OF THE EXPRESSION OF METALLOTHIONEIN IN FIVE TYPES EPITHELIUM CELL CANCER

来源 :中国癌症研究(英文版) | 被引量 : 0次 | 上传用户:jackiesage
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Objective: To study the expressions of metallothionein and the significances in cervical squamous cell cancer (CSC), bladder transitional cell cancer (BTC), esophageal squamous cell cancer (ESC), gastral tubular adenocarcinoma (GC) and large intestinal tubular adenocarcinoma (LIC). Methods: Immunohistochemical method was used to examine the expression rates of MT in five types of cancer tissue. Results: The expression rates of MT were 75.00% (24/32) in ESC, 52.27% (46/88) in GTC, 59.46% (44/74) in LIC, 64.86% (48/74) in BTC and 58.57% (41/70) in CSC respectively. The positive rates of MT expression were higher in low differentiation and deep muscular group than those in medium or high differentiation and superficial muscular invasion group (P<0.05). Conclusion: The expression of MT is related to differentiation degree and invasion degree.
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