脓毒症 (sepsis)是由感染所致的临床综合征 ,表现为发热或低热、白细胞增多或减少、心动过速、呼吸急促等 〔1〕。由严重的细菌感染所引起的脓毒症迄今仍然是世界范围内非心脏病重症监护患者的首位死亡原因〔2〕。据统计 ,在美国 ,每年有逾 4 0万例脓毒症患者 ,病死率可达35 % Sepsis is a clinical syndrome caused by infection, manifested as fever or hypothermia, increased or decreased leukocytosis, tachycardia, shortness of breath, etc. [1]. Sepsis caused by a serious bacterial infection is by far the first leading cause of death in non-cardiographically intensive care in the world (2). According to statistics, in the United States, there are more than 40 million sepsis patients each year, with a case fatality rate of 35%