论文部分内容阅读
目的 分析卵巢透明细胞腺癌的临床特点 ,探讨治疗及影响预后的因素。方法 对我院收治 2 2例卵巢透明细胞腺癌的临床资料进行回顾性分析。按 FIGO分期 : 期 15例 , 期 1例 , 期 5例 , 期 1例。治疗全部采用手术及化疗 ,4例加放疗。结果 2 2例中 ,1例失访 ,6例生存 <1年 ,11例 <3年 ,3例 >10年 ,5年生存率为 31.6 % (6 /19)。 期 5年生存率为 46 .2 % (6 /13) ,术后 2年内盆腔复发 7/15例 ,远处转移 4/15例。复发病人其淋巴结转移及实质性脏器转移分别为 6 /13例及 5 /13例。6 /2 1例合并有子宫内膜异位。结论 :卵巢透明细胞腺癌同卵巢上皮癌的其它亚型相比 ,更具有侵袭性 ,预后较差 ,其预后明显与分期 ,治疗方式及术后肿瘤残存有关 ,治疗以手术为主 ,并辅以化疗 ,配合放疗可减少复发 ,提高疗效。
Objective To analyze the clinical features of ovarian clear cell adenocarcinoma and explore the factors that influence the treatment and prognosis. Methods The clinical data of 22 cases of clear cell adenocarcinoma of the ovary in our hospital were retrospectively analyzed. According to FIGO staging: 15 cases, 1 case, 5 cases, 1 case. Treatments were all performed with surgery and chemotherapy, and 4 patients were treated with radiotherapy. Results Of the 22 cases, 1 was lost to follow-up, 6 survived <1 year, 11 cases <3 years, and 3 cases> 10 years. The 5-year survival rate was 31.6 % (6/19). The 5-year survival rate was 46.2% (6/13). The pelvic recurrence was 7/15 within 2 years after surgery and 4/15 distant metastases. The lymph node metastasis and substantial organ metastasis in relapsed patients were 6/13 and 5/13, respectively. 6/21 cases had endometriosis. Conclusion: Compared with other subtypes of ovarian epithelial carcinoma, ovarian clear cell adenocarcinoma is more invasive and has a poorer prognosis. Its prognosis is significantly related to staging, treatment methods, and residual tumor after surgery. The treatment is mainly surgery and supplemental. With chemotherapy, combined with radiotherapy can reduce recurrence and improve efficacy.