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目的:分析百草枯(PQ)中毒患者的年龄、性别因素,及时洗胃、血液净化治疗、抗炎和免疫抑制治疗对患者治疗效果的影响,为正确预防治疗PQ中毒、提高抢救成功率提供参考。方法:选取2006-01-2014-12在第四军医大学唐都医院急诊科就诊的PQ患者320例,对年龄、性别、临床表现、治疗方案及预后等临床资料进行回顾性分析。结果:1PQ中毒发病具有明显的年龄和性别分布,以青中年女性为主;2及时洗胃、导泻和血液净化治疗对PQ中毒的抢救成功率具有积极影响;3抗炎和免疫抑制治疗能够提高死亡患者的生存时间,但对死亡率无明显影响。结论:尽早洗胃、导泻及血液净化治疗对提高PQ中毒抢救成功率具有积极意义,抗炎和免疫抑制治疗能够提高死亡患者的生存时间。
OBJECTIVE: To analyze the influence of patients with paraquat (PQ) poisoning on age and sex, timely gastric lavage, blood purification, anti-inflammatory and immunosuppressive therapy on the treatment effect of patients, so as to provide a reference for the correct prevention and treatment of PQ poisoning and to improve the success rate of rescue. . Methods: A total of 320 PQ patients admitted to Emergency Department of Tangdu Hospital of the Fourth Military Medical University from January 2006 to December 2014 were retrospectively analyzed. Clinical data including age, sex, clinical manifestations, treatment regimen and prognosis were retrospectively analyzed. Results: The incidence of 1PQ poisoning had obvious age and sex distribution, mainly young and middle-aged women; 2 timely gastric lavage, catharsis and blood purification treatment had a positive impact on the success rate of rescue of PQ poisoning; 3 anti-inflammatory and immunosuppressive therapy Can increase the survival time of patients who died, but no significant impact on mortality. Conclusion: As soon as possible gastric lavage, cathartic and blood purification therapy to improve the success rate of PQ poisoning has a positive significance, anti-inflammatory and immunosuppressive therapy can increase the survival time of patients died.