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为探讨Ｅｐｓｔｅｉｎ－Ｂａｒ病毒在扁桃体炎、口腔癌中的感染状况，本研究利用聚合酶链反应（ＰＣＲ）和酶联免疫反应（ＥＬＩＳＡ）检测５４例正常人、２８例慢性扁桃体疾患者及３０例口腔癌患者的口腔含漱液、术后组织标本的ＥＢＶ－ＤＮＡ和血清标本的ＩｇＧ－ＥＢＶＣＡ，表明：扁桃体炎、口腔癌者的ＥＢＶ－ＤＮＡ检出率与正常人相比有显著性差异（Ｐ＜０．０５），而ＩｇＧ－ＥＢＶＣＡ的检出率与正常人相比无显著性差异（Ｐ＞０．０５），慢性扁桃体疾患者、口腔癌患者的含漱液与术后组织标本的ＥＢＶ－ＤＮＡ检出率相比无显著性差异（Ｐ＞０．０５），说明仅仅检测ＩｇＧ－ＥＢＶＣＡ较难反映患者的真实情况，检测口腔含漱液中的ＥＢＶ－ＤＮＡ能比较真实地反映ＥＢ病毒在扁桃体炎、口腔癌中的感染状况，在临床上有较高的应用价值
In order to investigate the infection status of Epstein-Bar virus in tonsillitis and oral cancer, 54 normal people, 28 chronic tonsillar disease patients and 30 patients with chronic tonsillar disease were detected by polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA) EBV-DNA in oral tissues and IgG-EBVCA in serum samples of oral cancer patients after mouthwash, postoperative tissue samples showed that the detection rate of EBV-DNA in tonsillitis and oral cancer patients was significantly different from that in normal people ( P <0.05). However, the detection rate of IgG-EBVCA was not significantly different from that of the normal controls (P> 0.05). Chronic tonsillar disease patients, mouthwash patients' EBV-DNA detection rate was no significant difference (P> 0.05), indicating that only the detection of IgG-EBVCA is more difficult to reflect the true situation of patients, detection of mouthwash EBV-DNA can more accurately reflect the EB Virus in tonsillitis, oral cancer in the infection status The higher the value