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目的:探讨覆膜血管支架对DebakeyⅢ型主动脉夹层患者的近、中期疗效及安全性。方法:选取我院收治的DebakeyⅢ型主动脉夹层患者46例,根据治疗方法的不同平均分为两组,对照组予以保守治疗,实验组予以覆膜血管支架置入进行治疗。手术后,观察并比较两组患者的术后一般情况、血液学指标、并发症的发生情况以及中期随访的情况。结果:术后,实验组患者的血常规,肝肾功能未见明显改变(P>0.05)。与治疗前相比,血清谷草转氨酶、谷丙转氨酶、肌酐、尿素氮、白细胞计数、血小板计数以及中性粒细胞百分含量水平升高显著(P<0.05);血清红细胞计数、血红蛋白含量、红细胞比积水平降低显著(P<0.05)。实验组的并发症发生率为13.04%显著低于对照组并发症发生率47.83%(P<0.05),实验组中期总有效率为95.65%显著高于对照组中期总有效率为65.22%,(P<0.05),差异均有统计学意义。结果:覆膜血管支架治疗DebakeyⅢ型主动脉夹层患者的近、中期疗效显著,安全性较高。
Objective: To investigate the short-term and long-term efficacy and safety of stent-graft in patients with Debakey Ⅲ aortic dissection. Methods: Forty-six patients with Debakey Ⅲ aortic dissection in our hospital were divided into two groups according to the average of the treatment methods. The control group was given conservative treatment. The experimental group was treated with the stent graft. After surgery, the postoperative general conditions, hematological indexes, the incidence of complications and the mid-term follow-up were observed and compared between the two groups. Results: After operation, there was no significant change in blood routine, liver and kidney function in experimental group (P> 0.05). Aspartate aminotransferase, creatinine, urea nitrogen, white blood cell count, platelet count and neutrophil percentage increased significantly (P <0.05) compared with those before treatment. Serum erythrocyte count, hemoglobin, The specific product level decreased significantly (P <0.05). The incidence of complications in the experimental group was significantly lower than that in the control group (13.04%, 47.83%, P <0.05). The total effective rate in the experimental group was 95.65%, which was significantly higher than that in the control group (65.22% P <0.05), the differences were statistically significant. Results: The treatment of Debakey Ⅲ aortic dissection with stent-graft was significant and safe in the near and medium-term.