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曼氏血吸虫的免疫病理损害包括在肝和肠组织中沿虫卵周围形成肉芽肿,肉芽肿的形成是由MHC-Ⅱ限制的CD4~+辅助性T细胞(Th)诱发的免疫病理反应。C3H小鼠感染后能形成显著的肉芽肿,Sm-p40分子是
The immunopathological damage of Schistosoma mansoni includes the formation of granulomas around the eggs in the liver and intestine. The formation of granulomas is an immunopathological response induced by MHC-II-restricted CD4 ~ + helper T cells (Th). C3H mice develop significant granulomas when infected, and the Sm-p40 molecule is