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目的研究右美托咪定的不同应用方式对小儿全身麻醉苏醒期的影响。方法将我院收治的80例行全身麻醉患儿随机分为对照组和实验组,各40例,均行全身诱导麻醉。拔管前给予对照组患儿静脉泵入右美托咪定,实验组气管导管注射右美托咪定。观察两组患儿右美托咪定应用后及拔管后心率、血压及呛咳情况。结果对照组患儿在右美托咪定应用5min后舒张压、心率均高于实验组,收缩压低于使实验组,差异有统计学意义(P<0.05);对照组拔管后舒张压、收缩压均低于实验组,心率高于实验组,差异有统计学意义(P<0.05);对照组患儿唤醒时间、气管拔管时间均高于实验组,差异有统计学意义(P<0.05);2组患儿呛咳评分无明显差异(P>0.05)。结论给予患儿静脉泵入、气管内注射右美托咪定均可稳定血压与心率,气管内注射可明显缩短唤醒时间与气管插管时间。
Objective To study the effect of different application modes of dexmedetomidine on general anesthesia recovery period in children. Methods 80 cases of general anesthesia admitted to our hospital were randomly divided into control group and experimental group, 40 cases in each group, all underwent general anesthesia induction. Patients in control group were given intravenous dexmedetomidine before extubation, dexmedetomidine was injected in tracheal catheter in experimental group. Two groups of children with dexmedetomidine after application and after extubation heart rate, blood pressure and cough. Results Compared with the experimental group, the diastolic blood pressure and heart rate of the control group were significantly lower than those of the experimental group (P <0.05). The diastolic blood pressure, Systolic blood pressure were lower than the experimental group, heart rate was higher than the experimental group, the difference was statistically significant (P <0.05); control group children wake time, tracheal extubation time were higher than the experimental group, the difference was statistically significant (P < 0.05). There was no significant difference in choking cough scores between the two groups (P> 0.05). Conclusion Intravenous injection of dexmedetomidine and intravenous injection can stabilize blood pressure and heart rate, and tracheal intubation can significantly shorten the wake-up time and intubation time.