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据报导,败酱科败酱(Patriina villosa Juss.) 的干馏物含有引诱猫的物质。本文对此活性成分进行了研究。根与根茎的甲醇提取物,经进一步化学分离和鉴定得到三个已知化合物:morroniside,loganin及甙元为石竹素(Oleanolic acid)的皂甙,同时得到一个新的化合物命名为villoside(Ⅰ)。 Villoside用吡啶醋酐乙酰化,得熔点112～113°无色结晶,分子式C_(24)H_(34)O_(12),以β-糖甙酶水解得3D-萄萄糖和甙元。经红外光谱、质谱及气相层析鉴定甙元为α-iridodiol。Villoside的结构为(Ⅰ),并由合成方法证实。
It has been reported that the carbonized chard of Patriina villosa Juss. Contains cat-luring substances. In this paper, the active ingredients were studied. Three known compounds were obtained by further chemical separation and identification of methanol extracts of roots and rhizomes: morroniside, loganin and aglycone of aglycones, and a new compound was named as villoside (Ⅰ). Villoside is acetylated with pyridine acetic anhydride to obtain colorless crystals with a melting point of 112 to 113 °. The molecular formula C 24 H 34 O 12 is hydrolyzed by β-glycosidase to obtain 3D-glucose and aglycon. The aglycone was identified as α-iridodiol by IR, MS and GC. The structure of Villoside is (Ⅰ) and confirmed by the synthetic method.