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研究发现,幽门螺杆菌(Hp)感染者在质子泵抑制剂治疗期间胃内pH值的升高明显大于无幽门螺杆菌感染者。由于胃食管反流疾病患者的愈合和症状的改善与治疗过程中胃内pH值的升高直接相关,因此可以假设,幽门螺杆菌感染的反流性食管炎患者用质子泵抑制剂治疗的效果较非感染者好。 病人和方法:采用双盲、按幽门螺杆菌感染状态平行分组的比较方法。研究对象为971例18岁以上经内镜证实的Ⅱ级和Ⅲ级(Savary/
The study found that Helicobacter pylori (Hp) infection during proton pump inhibitor treatment of gastric pH was significantly higher than those without H. pylori infection. Since healing and improvement of symptoms in patients with gastroesophageal reflux disease is directly linked to an increase in intragastric pH during treatment, it can be hypothesized that the effect of proton pump inhibitor treatment in patients with H.pylori -revailing reflux esophagitis Better than non-infected. Patients and Methods: A double-blind, parallel comparison of H. pylori infection status was used. The study object was 971 cases of endometrial proven grade Ⅱ and Ⅲ over 18 years old (Savary /