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用原子吸收分光光度计无焰原子吸收光谱法测定各期矽肺患者63例血清锰(Ma)。其含量在矽肺Ⅰ期、Ⅱ期、Ⅲ期分别为38.4×10_(?)~(-3)±21.2×10~(-3),31.4×10~(-3)±15.9×10~(-3),12.4×10_(M)~(-3)±4.6×10~(3-)μmol/L,均较正常对照组锰含量129.3×10~(-3)±1=54.6×10~(-3)为低,均有非常显著性差异(P<0.01)。讨论了矽肺患者血清Mn降低的原因可能与患者体内硅含量大量增加有关。提出了治疗措施宜着重使血清Mn水平升高,可能对矽肺患者有益。
Sixty-three patients with silicosis of serum manganese (Mn) were determined by flame atomic absorption spectrometry with atomic absorption spectrophotometer. The content of them in stage I, II and III of silicosis were 38.4 × 10 ~ (?) ~ (-3) ± 21.2 × 10 ~ (-3), 31.4 × 10 ~ (-3) ± 15.9 × 10 ~ 3, 12.4 × 10 -3 M × -3.6 × 10 -3 μmol / L, all of which were higher than that of the normal control group (129.3 × 10 -3 ± 1 = 54.6 × 10 ~ (-1) -3) is low, there is a very significant difference (P <0.01). It is discussed that the reason for the decrease of serum Mn in patients with silicosis may be related to the large increase of silicon content in patients. Proposed treatment should focus on the elevated levels of serum Mn may benefit patients with silicosis.