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目的比较口服相同剂量米非司酮后于不同时间阴道给予米索前列醇的流产效果。方法随机选取90例早孕妇女作为研究对象并进行分组比较。结果妊娠期限在≤49d、50～55d、56～60d的完全流产率差异无统计学意义(P>0.05)。口服100mg米非司酮24h和48h后阴道放置米索前列醇600ug后阴道流血发生率的差异有统计学意义(P<0.05),但阴道出血的时间在两组中的差异无统计学意义(P>0.05)。结论口服100mg米非司酮24h后于阴道放置米索前列醇的效果较好,值得临床推广及应用。
Objective To compare misoprostol misoprostol vaginal discharge at different times after oral administration of the same dose of mifepristone. Methods 90 cases of early pregnancy women were randomly selected as the study group and compared. Results There was no significant difference in the complete abortion rate of gestational age ≤49d, 50 ~ 55d, 56 ~ 60d (P> 0.05). The incidence of vaginal bleeding after oral administration of 100 mg mifepristone at 24h and 48h after vaginal misoprostol treatment was statistically significant (P <0.05), but there was no significant difference in the time of vaginal bleeding between the two groups ( P> 0.05). Conclusion Oral mifepristone 100mg 24h after vaginal placement of misoprostol better effect, worthy of clinical promotion and application.