谷氨酸是听觉系统最重要的传入神经递质,也有神经毒性作用,可特异性地损伤内毛细胞。本文重点综述谷氨酸的神经毒性作用及机制,以及听神经病的诸多病因,试图探讨谷氨酸的神经毒性对内耳的影响及听神经病诸多病因之间可能存在的相关性。1　谷氨酸神经兴奋性毒性损害的研究众所周 Glutamic acid is the most important afferent neurotransmitter in the auditory system and also has neurotoxic effects that specifically damage inner hair cells. This review focuses on the neurotoxic effects of glutamate and its mechanisms, as well as many causes of auditory neuropathy in an effort to explore the possible correlation between the neurotoxic effects of glutamate on the inner ear and many causes of auditory neuropathy. 1 glutamate nerve excitotoxicity damage research week