系统性白色念珠菌感染在小于1,500g的极低体重早产儿中是一常见而病死率又高的一种疾病。本病20年来文献报道共26例,作者报道5例、平均体重869g,作者结合文献,对本病的诊断和治疗进行了讨论。发病前均用过广谱抗生素,并经内导管给营养液。3例有霉菌全身性侵入的诱因;出生时体表有念球菌病灶和心内有真菌包块,手术切除者各2例,1例因肠闭锁而手术。5例均作皮肤、血、导管、 Systemic Candida albicans infection is a common and fatal disease in very low birth weight preterm infants less than 1,500 g. The disease in the past 20 years, a total of 26 cases reported in the literature, the authors reported in 5 cases, the average weight of 869g, the author combined with the literature on the diagnosis and treatment of the disease were discussed. Before the onset of broad-spectrum antibiotics have been used, and by the catheter to the nutrient solution. 3 cases of systemic inducement of fungi; birth at the table with a meningococcal focus and heart fungus mass, surgical resection in 2 cases, 1 case of intestinal atresia and surgery. 5 cases were made of skin, blood, catheter,