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[目的]探讨窄带成像放大内镜技术(NBI-ME)鉴别大肠肿瘤性病变与非肿瘤性病变的研究。[方法]本研究病例来源于我院内镜室2012年3月~2015年3月期间行结肠镜检查的413例患者,发现大肠新生物或息肉样病变者156例入选作为研究对象。分别采用普通内镜技术与NBI-ME内镜技术鉴别大肠肿瘤性病变与非肿瘤性病变准确性、特异性、敏感性及清晰度。[结果]NBI-ME内镜诊断肿瘤性病变准确性94.8%、特异性93.9%、敏感性94.3%,普通内镜诊断肿瘤性病变准确性68.5%、特异性71.2%、敏感性70.6%。NBI-ME内镜诊断肿瘤性病变准确性、特异性、敏感性均明显高于普通内镜(P<0.05);NBI-ME内镜检测微血管、腺管开口形态及病变轮廓清晰度评分均明显高于普通内镜,且差异有统计学意义(P<0.05)。[结论]NBI-ME鉴别大肠肿瘤性病变与非肿瘤性病变准确性高、特异性高、敏感性高,且能够更清晰地显示微血管形态、腺管开口形态及病变轮廓,故而该技术具有重要诊断鉴别意义。
[Objective] To explore the narrow-band imaging magnifying endoscopy (NBI-ME) to identify colorectal neoplasms and non-neoplastic lesions. [Methods] The cases of this study originated from 413 patients who underwent colonoscopy during the period from March 2012 to March 2015 in our hospital. A total of 156 cases of newly diagnosed neoplasms or polypoid lesions were enrolled in this study. The common endoscopic technique and NBI-ME endoscopy were used to identify the accuracy, specificity, sensitivity and clarity of colorectal neoplasms and non-neoplastic lesions respectively. [Results] The diagnostic accuracy of NBI-ME was 94.8%, 93.9%, 94.3%, 68.5%, 71.2% and 70.6% respectively. The accuracy, specificity and sensitivity of NBI-ME endoscopy in diagnosing neoplastic lesions were significantly higher than those of ordinary endoscopy (P <0.05). The open endoscopic examination of NBI-ME microvascular and ductal structures showed significant differences Higher than ordinary endoscopy, and the difference was statistically significant (P <0.05). [Conclusion] The technique of NBI-ME in differentiating colorectal neoplasms from non-neoplastic lesions has high accuracy, specificity and sensitivity, and can clearly show the morphology of microvessels, the shape of the open duct and the contour of the lesion. Therefore, this technique is important Diagnostic differential significance.