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我们遇到以“尿崩症”为首先表现及弥散性骨质硬化的多发性骨髓瘤两例报告如下。例1,男性,55岁。因烦渴,多饮,多尿半个月住内分泌科检查:CT 蝶鞍片未见异常。以顽固性低比重尿诊断:垂体性尿崩症。经P607,双克等治疗以后症状好转出院。2个月后上述症状加重再次入院。查体:中度贫血貌,余无阳性体征。实验室检查:Hb71g/L,WBC4.1×10~9/L,Fer:464.8ug/ul,X 摄片头颅骨可见多个穿凿样骨质破坏区,大小不等。免疫球蛋白:IgG∶21.6g/L。临床诊断:多发性骨髓瘤IgG 型。予MP(马法兰+强的松)方案治疗3个
We met with “diabetes insipidus” as the first performance and disseminated multiple sclerosis of multiple myeloma reported as follows. Example 1, male, 55 years old. Due to polydipsia, drink more urine and urine for half a month to live Endocrinology examination: CT sella no abnormalities. Urinary diagnosis of intractable low proportion: diabetes pituitary diabetes insipidus. After P607, two grams and other symptoms improved after treatment was discharged. After 2 months, the above symptoms increased again hospitalized. Physical examination: moderate anemia appearance, I no positive signs. Laboratory tests: Hb71g / L, WBC4.1 × 10 ~ 9 / L, Fer: 464.8ug / ul, X radiograph skull visible multiple wear chisel bone destruction area, the size range. Immunoglobulin: IgG: 21.6 g / L. Clinical diagnosis: multiple myeloma IgG type. To MP (melphalan + prednisone) program for the treatment of three