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目的了解安阳市2012年手足口病病原感染情况及流行特征,为下一阶段防控工作提供科学依据。方法采用实时荧光PCR方法对安阳市手足口病例样品进行肠道病毒鉴定和分型,使用SPSS 19.0软件对数据进行统计学分析。结果 2012年安阳市手足口病病例以EV71型肠道病毒感染为主(46.11%),CA16型(8.37%)和其他肠道病毒(11.48%)占有一定比例。夏季EV71型感染最为显著,感染人群主要是低龄婴幼儿,性别间差异无统计学意义(P>0.05)。对全市9个县区聚类分析发现,城镇地区以EV71型感染为主,农村地区则以非EV71和CA16的其他型肠道病毒感染为主。结论安阳地区2012年手足口疫情较2011年呈现出EV71感染增高的趋势。应将防治EV71型感染作为遏制疫情上升的关键,并根据城镇和农村不同的疫情特点,制定和采取更有针对性的防控策略和措施。
Objective To understand the prevalence and epidemic characteristics of HFMD in Anyang in 2012 and provide a scientific basis for prevention and control in the next phase. Methods The real-time fluorescent PCR method was used to identify and type enterovirus in hand, foot and mouth in Anyang City. The data were analyzed by SPSS 19.0 software. Results In 2012, cases of HFMD in Anyang City were predominantly infected with EV71 (46.11%), while CA16 (8.37%) and other enteroviruses (11.48%) accounted for a certain proportion. EV71 infection in summer is the most significant, and the infected population is mainly young infants, the difference was not statistically significant (P> 0.05). Cluster analysis of 9 counties in the city found that EV71 was predominant in urban areas and other types of enterovirus infections were non-EV71 and CA16 in rural areas. Conclusion The 2012 hand-foot-mouth epidemic in Anyang area showed a trend of higher EV71 infection than that in 2011. The prevention and treatment of EV71 infection should be the key to curbing the rise of the epidemic and to formulate and adopt more targeted prevention and control strategies and measures based on the different epidemic characteristics in urban and rural areas.