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Objective To investigate the effects of tumor necrosis factor-α(TNF-α)monoclonal antibody on nuclear factor-κB(NF-κB)activation and inducible nitric oxide synthase(iN OS)expression in rats with pulmonary fibrosis induced by silica dust.Methods A total of 48 male Wistar rats were randomly divided into intervention group,silica dust exposure group,and control group,with 16 rats in each group.The rats in the intervention
Objective To investigate the effects of tumor necrosis factor-α (TNF-α) monoclonal antibody on nuclear factor-κB (activation and inducible nitric oxide synthase (iN OS) expression in rats with pulmonary fibrosis induced by silica dust. Methods A total of 48 male Wistar rats were randomly divided into an intervention group, silica dust exposure group, and control group, with 16 rats in each group. The rats in the intervention