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目的观察硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压的临床效果。方法选择2012年10月~2013年10月来本院治疗老年2型糖尿病肾病合并高血压患者160例,随机将160例分成对照组80例,治疗组80例。对照组患者采用硝苯地平控释片治疗,治疗组患者在对照组治疗基础上联合缬纱坦治疗。观察两组患者治疗效果。结果通过治疗,两组患者的血压、血糖均明显下降,但是治疗组患者的血压下降率明显高于对照组患者,差异有统计学意义(P<0.05)。治疗组患者的治疗有效率明显高于对照组患者,差异有统计学意义(P<0.05)。结论采用硝苯地平控释片联合缬沙坦治疗老年2型糖尿病肾病合并高血压效果明显,能提高治愈率,降低无效率,值得临床推广应用。
Objective To observe the clinical effect of nifedipine controlled release tablets combined with valsartan in the treatment of elderly type 2 diabetic nephropathy complicated with hypertension. Methods From October 2012 to October 2013, 160 patients with type 2 diabetic nephropathy complicated with hypertension were treated in our hospital. Totally 160 cases were divided into control group (80 cases) and treatment group (80 cases). Patients in the control group were treated with nifedipine controlled release tablets. Patients in the treatment group were treated with valosemiol on the basis of the control group. Observation of two groups of patients treatment effect. Results After treatment, the blood pressure and blood glucose in both groups were significantly decreased, but the rate of decline in blood pressure in the treatment group was significantly higher than that in the control group (P <0.05). The treatment group patients with treatment efficiency was significantly higher than the control group patients, the difference was statistically significant (P <0.05). Conclusion The use of nifedipine controlled release tablets combined with valsartan in the treatment of elderly type 2 diabetic nephropathy with hypertension has obvious effect, which can improve the cure rate and reduce the inefficiency, which is worthy of clinical application.