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目的:分析使用缺血修饰白蛋白(IMA)早期诊断对急性心肌缺血患者的效果。方法:选取患者400例以及100例正常者,分为5组,上述5组患者使用白蛋白钴结合试验方法检测,检测项目为血浆IMA水平、心脏肌钙蛋白I水平及心电图。结果:在临界值等于0.45 ABSU的时候,IMA检测具有最佳的正确诊断指数、阴性预测值、敏感性、特异性。综合征组、高压组、心肌炎组、胸痛组的IMA水平明显高于对照组,同时在阳性率方面,组间比较,差异具有统计学意义(P<0.05)。结论:对患者使用IMA早期诊断可以取得非常显著的诊断效果,在急性心肌缺血患者诊断过程中发挥着显著作用。
Objective: To analyze the effect of early diagnosis of acute myocardial ischemia using ischemia modified albumin (IMA). Methods: 400 patients and 100 healthy controls were selected and divided into 5 groups. The above 5 groups of patients were detected by albumin cobalt binding assay, and the test items were plasma IMA, cardiac troponin I and ECG. RESULTS: The IMA test had the best correct diagnostic index, negative predictive value, sensitivity, specificity at a cutoff of 0.45 ABSU. IMA levels in syndrome group, high-pressure group, myocarditis group and chest pain group were significantly higher than those in control group. There was also significant difference in the positive rate between the two groups (P <0.05). Conclusion: The early diagnosis of patients with IMA can be obtained very significant diagnostic results in the diagnosis of acute myocardial ischemia patients play a significant role.