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作者对1984年到1992年6月30日向 法国地方药物监控中心和巴斯德血清及疫苗制造厂的药物监控部门报告的麻疹、腮腺炎或风疹疫苗接种后发生的血小板减少性紫癜(TP)作了回顾性调查,评价了疫苗接种后的发病率和特征.八年间共报告了60例发生于疫苗接种后2~45天的急性TP,患者年龄为1~11岁,其中出现在麻疹、腮腺炎和风疹(MMR)三联疫苗接种后42例,麻疹、风疹二联疫苗接种后12例,风疹疫苗接种后4例,麻疹疫苗接种后2例.每10万剂疫苗接种后TP发病率分别为风疹0.17,麻疹0.23,麻疹、风疹二联疫苗0.87,MMR疫苗0.95.1984~1992年每年发病例数分别为:2、4、7、7、6、1、
The authors report that thrombocytopenic purpura (TP) occurred after measles, mumps or rubella vaccination reported to the drug regulatory authorities of the French local drug control center and the Pasteur Serum and Vaccine Factory between 1984 and June 30, 1992 A retrospective survey was conducted to evaluate the incidence and characteristics of the vaccine after vaccination.60 acute TPs occurred 2 to 45 days after vaccination over a period of eight years, ranging in age from 1 to 11 years, with measles, parotid gland 42 cases after inflammation and rubella (MMR) triple vaccination, 12 cases after measles and rubella vaccination, 4 cases after rubella vaccination and 2 cases after measles vaccination.The incidence of TP after every 100,000 vaccination were Rubella 0.17, measles 0.23, measles, rubella two vaccine 0.87, MMR vaccine 0. 95. 1984 to 1992 the annual incidence of cases were: 2,4,7,7,6,1,