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目的 :旨在探讨血锌原卟啉 (ZPP)与血红蛋白 (Hb)及血清铁蛋白 (SF)的关系 ,以便揭示出ZPP在诊断铁缺乏中的价值。方法 :对 617例小学生测定了Hb、ZPP和SF ,筛选 42 9例正常儿童 ,74例铁缺乏患儿及 5 5例缺铁性贫血患儿 ,检测ZPP、Hb、SF ,对后两项数值与ZPP相关性进行对照分析。结果 :正常儿童与铁缺乏儿童ZPP均数之间有高度显著性差异 (P <0 .0 1)。不同缺铁阶段随着缺铁程度加重 ,ZPP与Hb及SF之间呈高度负相关 (P <0 .0 1)。结论 :ZPP升高可作为诊断铁缺乏的可靠指标
Objective: To explore the relationship between ZPP and hemoglobin (Hb) and serum ferritin (SF) in order to reveal the value of ZPP in the diagnosis of iron deficiency. Methods: Hb, ZPP and SF were measured in 617 pupils, 429 normal children, 74 iron deficient children and 55 children with iron deficiency anemia were screened. ZPP, Hb and SF were detected. ZPP correlation analysis. Results: There was a highly significant difference in the mean number of ZPP between normal children and iron-deficient children (P <0.01). In the different stages of iron deficiency, with the aggravation of the iron deficiency, there was a highly negative correlation between ZPP and Hb and SF (P <0.01). Conclusion: Elevated ZPP can be used as a reliable indicator of iron deficiency